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Dr. Merrill Garnett Bio | Scientific Research | View Videos


 


"Increased Pseudoinductance in Paired Mixtures of Biopolymers is a Model for Twin Wire Mutual Inductance in RNA and DNA"
(Garnett and Remo, 198th Meeting of Electrochemical Society, Abstract 1152, Phoenix 2000)

Garnett McKeen Laboratory, Inc.
150 Islip Avenue, Suite 6
Isilp, NY 11751

While not common, inductance in liquids (pseudoinductance = corrosion production of a magnetic field) has been studied (1,2) in molten salts. Impedance plots of pseudoinductive material yield a clockwise circular loop extending from the electrolyte arc in the complex plane. The lower part of this loop represents phase reversal and the current lag typical of inductance (Figs. 1a,1b). Current lags voltage.

We observe rudimentary pseudoinductancein calf liver RNA, calf thymus DNA (Sigma), and hyaluronic acid (Hyal Corp.). Such small inductance loops (Figs. 2a,2b,2c) are variable, abortive, tend to scatter-plot, and are difficult to reproduce. All responses are measured in purged, aqueous 0.1 M Na acetate at pH 5.2 at a DC current of 0.5 V., using a Hg working electrode---this is the ion pump of the reaction (Hg +1)---and an Ecochemie electro-analytic system at room temperature.

Subsequent measurements indicate addition of hyaluronic acid to either DNA or RNA regularly produces large continuous pseudoinductance responses (Figs. 1a,1b). These spectra initially suggest additive effects. However the new smoothness and reproducibility raise a question. Are there electronic interactions between those weakly inductive linear polymers expressing clear voltammetric signals, which intermingle in bio-systems? Are we wired?

Subsequent experiments using gamma globulin as a control at a variety of DC voltages show this globulin alone produces a poorly developed capacitance plot (Fig. 3a). Globulin and hyaluronic acid combined produce a well developed capacitance plot; the loop is reliably interrupted at the critical point before phase reversal and is not additive (Fig. 3b). Plots were linear at 0.16 V. It appears that such mixtures of hyaluronic acid with another bipolymer are electronically interactive. This suggests that twin wire-like impedance in liquids occurs, analogous to twin solid wire cables with flux coupling and mutual reactance (3). Such a process would enable long range energy transfer in liquids and signals between cells in the living state.

References:
1. Franischetti, D.R., Macdonald, J.R. J.Electroanal.Chem., V.100,583-605 (1979).

2. Bai, L., Conway, B.E., Electrochimica.Acta, V.18,No.14, 1803-1815, (1993).

3. Kim, s., Neikirk, D.P., IEEE-MTT-S Intl. Microwave Symp., R.G. Ranson (ed.), V.3, 1815-1818, (june 1996).



 
 

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